![AffiAB® Anti-VEGF Receptor 2 Antibody [SU03-42]](/web/image/product.product/89287/image_1024/%5BAFG-HB-4073%5D%20AffiAB%C2%AE%20Anti-VEGF%20Receptor%202%20Antibody%20%5BSU03-42%5D%20?unique=a48b62f)
AffiAB® Anti-VEGF Receptor 2 Antibody [SU03-42]
Kinase insert domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor. KDR is the human gene encoding it. KDR has also been designated as CD309 (cluster of differentiation 309) . KDR is also known as Flk1 (Fetal Liver Kinase 1) . The Q472H germline KDR genetic variant affects VEGFR-2 phosphorylation and has been found to associate with microvessel density in NSCLC.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P35968 Human; SwissProt: O08775 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
SU03-42
KO/KD
N/A
Species reactivity
Human, Rat
Tested applications
WB, IF-Cell, IHC-P, IP
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human VEGF Receptor 2 aa 30-630 / 1, 356.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
VEGF signaling pathway, PI3K-AKT, Cancer, Cardiovascular, Immunology & Inflammation
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:50-1:200; IHC-P: 1:50-1:100; IP: Use at an assay dependent concentration.
Molecular Weight
Predicted band size: 152 kDa
Subcellular location
Cytoplasm, Nucleus, Cell junction, Endoplasmic reticulum, Cell membrane, Early endosome, Secreted.
Positive control
A431, HUVEC, PMVEC, human placenta tissue, human kidney tissue.