AffiAB® Anti-VCP Antibody
Valosin-containing protein (VCP) is a highly conserved, that belongs to the AAA (ATPase associated with a variety of cellular activities) family of proteins. It is necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. VCP is involved in the formation of the transitional endoplasmic reticulum (tER) . VCP homo-hexamers associate with a variety of protein cofactors to form many distinct protein complexes, which act as chaperones to unfold proteins and transport them to specific cellular compartments or to the proteosome.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P55072 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Zebrafish
Tested applications
WB, IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within residues of VCP aa 757-806 / 806.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Neuroscience, Amyotrophic lateral sclerosis
Recommended dilutions
WB: 1:2, 000; IF-Cell: 1:200; IHC-P: 1:200
Molecular Weight
89 kDa
Subcellular location
Cytoplasm, nucleus, endoplasmic reticulum
Positive control
L929, F9, SW480, A549, MCF-7, Hela, NIH/3T3, N2A, Jurkat, HepG2, A431, mouse brain tissue, mouse heart tissue, mouse liver tissue, mouse kidney tissue, human uterus tissue, SHG-44 cells , mouse skeletal muscle tissue .