AffiAB® Anti-VCAM1 Antibody [SA05-04]
Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106) is a protein that in humans is encoded by the VCAM1 gene. VCAM-1 functions as a cell adhesion molecule. The VCAM-1 protein mediates the adhesion of lymphocytes, monocytes, eosinophils, and basophils to vascular endothelium. It also functions in leukocyte-endothelial cell signal transduction, and it may play a role in the development of atherosclerosis and rheumatoid arthritis.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P19320 Human; SwissProt: P29533 Mouse; SwissProt: P29534 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
SA05-04
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P, IP
Predicted species reactivity
Rat, Zebrafish
Immunogen
Synthetic peptide within Human VCAM1 aa 690-739 / 739.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Cancer, Immunology & Inflammation, NF-KB signaling pathway
Recommended dilutions
WB: 1:500; IF-Cell: 1:50; IF-Tissue: 1:50; IHC-P: 1:200; IP: Use at an assay dependent concentration.
Molecular Weight
Predicted band size: 81 kDa
Subcellular location
Membrane
Positive control
Human spleen tissue lysate, NIH/3T3 cell lysate, HUVEC, human tonsil tissue, human spleen tissue, mouse spleen tissue.