AffiAB® Anti-USP39 Antibody [JE60-87]
Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q53GS9 Human; SwissProt: Q3TIX9 Mouse; SwissProt: B2GV41 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE60-87
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, IF-Cell
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human USP39 aa 466-565/565.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000; IHC-P: 1:50-1:200; IF-Cell: 1:50-1:100
Molecular Weight
65 kDa
Subcellular location
Nucleus.
Positive control
Hela cell lysate, 293T cell lysate, K562 cell lysate, rat testis tissue, human colon tissue, human colon carcinoma tissue, human prostate tissue, human prostate carcinoma tissue, human uterus tissue, mouse kidney tissue, 293T, A549, Hela.