AffiAB® Anti-USP39 Antibody [JE59-07]
Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q53GS9 Human; SwissProt: Q3TIX9 Mouse; SwissProt: B2GV41 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE59-07
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human USP39 aa 151-350/565.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000
; IHC-P: 1:50-1:200
Molecular Weight
65 kDa
Subcellular location
Nucleus.
Positive control
Hela and Jurkat cell lysates, rat brain tissue, human colon carcinoma tissue, human breast carcinoma tissue, mouse kidney tissue.