AffiAB® Anti-USP36 Antibody
Ubiquitin-specific protease 36 is an enzyme that in humans is encoded by the USP36 gene. This gene encodes a member of the ubiquitin-specific protease family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the nucleoli and deubuquitinate nucleophosmin and fibrillarin. May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4) .
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q9P275 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human USP36 aa 1, 074-1, 123 / 1, 123.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
IF-Cell: 1:50-1:200; IHC-P: 1:50-1:200
Molecular Weight
123 kDa
Subcellular location
Nucleus.
Positive control
A549, Hela, LOVO, human liver cancer tissue, human spleen tissue.