![AffiAB® Anti-ULBP1 Antibody [JE65-75]](/web/image/product.product/89229/image_1024/%5BAFG-HB-4014%5D%20AffiAB%C2%AE%20Anti-ULBP1%20Antibody%20%5BJE65-75%5D%20?unique=b83e256)
AffiAB® Anti-ULBP1 Antibody [JE65-75]
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D) , an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q9BZM6 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE65-75
KO/KD
N/A
Species reactivity
Human
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human ULBP1 aa 1-50/244.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000
Molecular Weight
Predicted band size: 28 kDa
Subcellular location
Cell membrane, Endoplasmic reticulum, Membrane.
Positive control
SiHa cell lysates, Jurkat cell lysates.