AffiAB® Anti-UFO Antibody [C4-A8]

https://www.affiab.com/web/image/product.template/116394/image_1920?unique=315d7a9
(0 review)

CAT# AFG-HB-4010
Size: 100 μL

465.00 465.0 USD 465.00

465.00

For Price Contact info@affigen.com

This combination does not exist.

Terms and Conditions
30-day money-back guarantee
Shipping: 2-3 Business Days

AffiAB® Anti-UFO Antibody [C4-A8]

Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. AXL receptor tyrosine kinase has been shown to interact with TENC1.Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.

Antibody type

Mouse monoclonal Antibody

Uniprot ID

SwissProt: P30530 Human

Recombinant

NO

Conjugation

Non-conjugated

Host

Mouse

Isotype

IgG1

Clone

C4-A8

KO/KD

N/A

Species reactivity

Human

Tested applications

WB, IF-Cell

Predicted species reactivity

N/A

Immunogen

Recombinant protein with Human UFO aa 10-160 / 894.

Storage

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2 mg/mL.

Purity

Protein G affinity purified.

Signal pathway

N/A

Recommended dilutions

WB: 1:500; IF-Cell: 1:200-1:500

Molecular Weight

Predicted band size: 98 kDa

Subcellular location

Cell membrane.

Positive control

Recombinant protein lysate, SW480, LOVO.