![AffiAB® Anti-UFC1 Antibody [JE65-12]](/web/image/product.product/89223/image_1024/%5BAFG-HB-4008%5D%20AffiAB%C2%AE%20Anti-UFC1%20Antibody%20%5BJE65-12%5D%20?unique=b83e256)
AffiAB® Anti-UFC1 Antibody [JE65-12]
E1-like enzyme which specifically catalyzes the second step in ufmylation. Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q9Y3C8 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE65-12
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human UFC1 aa 1-150/167.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000; IF-Cell: 1:400; IHC-P: 1:400
Molecular Weight
Predicted band size: 19 kDa
Subcellular location
Extracellular exosome.
Positive control
293T cell lysates, SH-SY5Y, human trachea tissue, human breast carcinoma tissue.