AffiAB® Anti-Tropomodulin 2 Antibody [JE53-06]
Tropomodulin 2 (neuronal) also known as TMOD2 is a protein which in humans is encoded by the TMOD2 gene. This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q9NZR1 Human; SwissProt: Q9JKK7 Mouse; SwissProt: P70566 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE53-06
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human Tropomodulin 2 aa 1-108 / 351.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB:1:500-1:2, 000; IF-Cell:1:50-1:100; IHC-P:1:50-1:200
Molecular Weight
Predicted band size: 40 kDa
Subcellular location
Cytoplasm, Cytoskeleton.
Positive control
Rat brain tissue lysates, SiHa, rat spinal cord tissue, rat brain tissue, mouse brain tissue, mouse cerebellum tissue.