![AffiAB® Anti-TPPP Antibody [JE47-35]](/web/image/product.product/89128/image_1024/%5BAFG-HB-3908%5D%20AffiAB%C2%AE%20Anti-TPPP%20Antibody%20%5BJE47-35%5D%20?unique=d31c23b)
AffiAB® Anti-TPPP Antibody [JE47-35]
Tubulin polymerization-promoting protein is a protein that in humans is encoded by the TPPP gene. May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown. This protein has been linked to multiple sclerosis myelin lesions and CSF abnormalities in multiple sclerosis patients. This has also been linked to Parkinson's and Alzheimer's Disease.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: O94811 Human; SwissProt: Q7TQD2 Mouse; SwissProt: D3ZQL7 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE47-35
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human TPPP aa 80-185 / 219.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB:1:1, 000-1:2, 000
; IHC-P:1:50-1:200
; FC:1:50-1:100
Molecular Weight
Predicted band size: 24 kDa
Subcellular location
Cytoplasm. Cytoskeleton. Nucleus
Positive control
Mouse brain tissue lysates, rat brain tissue, human pancreas tissue, human uterus tissue, SHG-44.