AffiAB® Anti-TMEM192 Antibody [JE64-89]
TMEM192 is a widely expressed, four transmembrane protein that localizes to late endosomal/lysosomal membranes. This localization is mediated by two dileucine motifs present at the amino-terminus of TMEM192. A cysteine residue near the carboxy residue is responsible for disulfide bond formation in TMEM192 homodimers. Little is known about the function of this protein.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q8IY95 Human; SwissProt: Q9CXT7 Mouse; SwissProt: Q5U1Y0 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE64-89
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human TMEM192 aa 1-271/271.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500
; IHC-P: 1:100-1:400
Molecular Weight
Predicted band size: 31 kDa
Subcellular location
Late endosome, Lysosome membrane.
Positive control
HL-60 cell lysate, SK-Br-3 cell lysate, rat kidney tissue, human prostate carcinoma tissue, mouse small intestine tissue.