![AffiAB® Anti-TMED9 Antibody [A9A8]](/web/image/product.product/89087/image_1024/%5BAFG-HB-3862%5D%20AffiAB%C2%AE%20Anti-TMED9%20Antibody%20%5BA9A8%5D%20?unique=b83e256)
AffiAB® Anti-TMED9 Antibody [A9A8]
Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q9BVK6 Human; SwissProt: Q99KF1 Mouse; SwissProt: Q5I0E7 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
A9A8
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human TMED9 aa 31-220 / 235.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:5, 000-1:10, 000
; IHC-P: 1:200
Molecular Weight
Predicted band size: 27 kDa
Subcellular location
Endoplasmic reticulum membrane, Golgi apparatus, Endoplasmic reticulum-Golgi intermediate compartment membrane.
Positive control
Hela cell lysate, THP-1 cell lysate, A549 cell lysate, MCF-7 cell lysate, PC-12 cell lysate, NIH/3T3 cell lysate, mouse liver tissue lysate, mouse lung tissue lysate, HepG2 cell lysate, LO2 cell lysate, human liver tissue lysate, rat liver tissue lysate, mouse liver tissue.