![AffiAB® Anti-Tissue Factor Antibody [SN20-16]](/web/image/product.product/89077/image_1024/%5BAFG-HB-3852%5D%20AffiAB%C2%AE%20Anti-Tissue%20Factor%20Antibody%20%5BSN20-16%5D%20?unique=a48b62f)
AffiAB® Anti-Tissue Factor Antibody [SN20-16]
Tissue factor, also called platelet tissue factor, factor III, or CD142, is a protein encoded by the F3 gene, present in subendothelial tissue and leukocytes. Its role in the clotting process is the initiation of thrombin formation from the zymogen prothrombin. Thromboplastin defines the cascade that leads to the activation of factor X—the tissue factor pathway. In doing so, it has replaced the previously named extrinsic pathway in order to eliminate ambiguity.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P13726 Human; SwissProt: P20352 Mouse; SwissProt: P42533 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
SN20-16
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P
Predicted species reactivity
Rat
Immunogen
Synthetic peptide within human Tissue Factor aa 30-70.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Immunology & Inflammation, Cardiovascular
Recommended dilutions
WB: 1:500-1:5, 000; IF-Cell: 1:100-1:500; IF-Tissue: 1:100-1:500; IHC-P: 1:100-1:500
Molecular Weight
Predicted band size: 33 kDa
Subcellular location
Membrane, screted.
Positive control
Mouse brain tissue lysate, U937 cell lysate, SH-SY5Y cell lysate, PANC-1, SHG-44, SH-SY5Y, human pancreas tissue, human breast carcinoma tissue, mouse pancreas tissue.