AffiAB® Anti-TGF beta 1 Antibody
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P01137 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human TGF beta 1 aa 20-210.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB:1:500
Molecular Weight
Predicted band size: 44 kDa.
Subcellular location
Extracellular matrix, Secreted.
Positive control
PC-3 cell lysate, A549 cell lysate, U87 cell lysate, Hela cell lysate, K562 cell lysate.