AffiAB® Anti-TESPA1 Antibody
TESPA1 (Thymocyte-expressed positive selection-associated protein 1) is required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. It plays a role in T-cell antigen receptor (TCR) -mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: A2RU30 Human; SwissProt: Q3U132 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human TESPA1 aa 221-270 / 521 (F249E) .
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:200; IHC-P: 1:50; FC: 1:50-1:100
Molecular Weight
Predicted band size: 59 kDa
Subcellular location
Cytoplasm. Membrane, Endoplasmic reticulum, Signalosome.
Positive control
Human thymus tissue lysate, mouse thymus tissue lysate, human liver tissue lysate, A431 cell lysate, A172, rat brain, human lung cancer, mouse brain, HepG2.