AffiAB® Anti-Tenascin C Antibody [SU36-01]
Tenascin C (TN-C) is a glycoprotein that in humans is encoded by the TNC gene. Expression of TN-C changes from development to adulthood. TN-C is highly expressed during embryogenesis and is briefly expressed during organogenesis, while in developed organs, expression is absent or in trace amounts. In the developing central nervous system, TN-C is involved in regulating the proliferation of both oligodendrocyte precursor cells and astrocytes. The regulation of TN-C is induced or repressed by a number of different factors that are expressed during embryonic tissue, as well as developed tissues during remodeling, injured, or neoplastic.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P24821 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
SU36-01
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human Tenascin C aa 2, 152-2, 201 / 2, 201.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
PI3K-AKT
Recommended dilutions
WB: 1:500-1:1, 000
; IHC-P: 1:50-1:400
; FC: 1:50-1:100
Molecular Weight
Predicted band size: 241 kDa
Subcellular location
Extracellular matrix.
Positive control
Human tonsil tissue, SH-SY5Y.