AffiAB® Anti-TEAD4 Antibody
TEF-3, also known as TEAD4 (TEA domain family member 4) , RTEF1, EFTR-2, TEFR-1, TCF13L1 or hRTEF-1B, is a 427 amino acid member of the transcriptional enhancer factor (TEF) family of proteins that are characterized by the presence of a TEA DNA-binding domain. Localized to the nucleus and expressed primarily in skeletal muscle, TEF-3 functions as a transcriptional regulator by binding specifically and non-cooperatively to the M-CAT motif found in the promotors of muscle-specific genes, thereby directing their subsequent expression. TEF-3 contains one TEA DNA-binding domain and is expressed as multiple isoforms due to alternative splicing events.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q15561 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human TEAD4 aa 57-121.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Cardiovascular
Recommended dilutions
WB: 1:500-1:1, 000
; FC: 1:50-1:100
Molecular Weight
Predicted band size: 48 kDa
Subcellular location
Nucleus.
Positive control
Hela cell lysate, human lung tissue lysate, human placenta tissue lysate, HepG2 cell lysate, LOVO.