AffiAB® Anti-TCP1 delta Antibody
Component of the chaperonin-containing T-complex (TRiC) , a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444) . As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable) .
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P50991 Human; SwissProt: P80315 Mouse; SwissProt: Q7TPB1 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human TCP1 delta aa 200-500 / 539.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000; IF-Cell: 1:50-1:200; IHC-P: 1:400; FC: 1:500-1:1, 000
Molecular Weight
Predicted band size: 58 kDa
Subcellular location
Cell projection, Cytoplasm, Cytoskeleton.
Positive control
Hela cell lysate, NIH/3T3 cell lysate, HepG2 cell lysate, rat testis tissue lysate, SW620, rat bladder tissue, human breast carcinoma tissue, SiHa, Hela.