![AffiAB® Anti-Syndecan 1 Antibody [JM11-21]](/web/image/product.product/88978/image_1024/%5BAFG-HB-3746%5D%20AffiAB%C2%AE%20Anti-Syndecan%201%20Antibody%20%5BJM11-21%5D%20?unique=a48b62f)
AffiAB® Anti-Syndecan 1 Antibody [JM11-21]
Syndecan-1 (SYND1) , also designated CD138, is a type I integral membrane proteoglycan that contains both chondroitin sulfate and heparan sulfate groups. It is expressed in mouse on pre-B cells, immature B cells and plasma cells. Syndecan-1 is also found on the basolateral surfaces of epithelial cells, endothelial cells of sprouting capillaries and embryonic condensing mesenchymal cells. Syndecan-1 functions as an extracellular matrix receptor which binds to collagens, Fibronectin and Thrombospondin. It has been shown to co-localize with Actin-rich filaments and may act to link the cytoskeleton to the extracellular matrix.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P18827 Human; SwissProt: P18828 Mouse; SwissProt: P26260 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JM11-21
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P
Predicted species reactivity
Rat
Immunogen
Recombinant protein within Human Syndecan 1 aa 13-274 / 310.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Cancer, Immunology & Inflammation, Neuroscience
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:100-1:500; IF-Tissue: 1:100-1:500; IHC-P: 1:50-1:200
Molecular Weight
Predicted band size: 32 kDa
Subcellular location
Membrane, Secreted.
Positive control
Human placenta tissue lysate, NIH/3T3 cell lysate, A431, Hela, HepG2, human tonsil tissue, human kidney tissue, human lung tissue, mouse colon tissue, mouse prostate tissue.