AffiAB® Anti-SV2B Antibody [A4C1]
Synaptic vesicle glycoprotein 2B is a protein that in humans is encoded by the SV2B gene.Probably plays a role in the control of regulated secretion in neural and endocrine cells.By similarity (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA) ; glycosylation is not essential but enhances the interaction . Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q7L1I2 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
A4C1
KO/KD
N/A
Species reactivity
Human, Rat
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human SV2B aa 400-600.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/ml.
Purity
Protein G affinity purified.
Signal pathway
Neuroscience
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:50-1:100; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
Predicted band size: 77 kDa.
Subcellular location
Cell junction, Cytoplasmic vesicle, Membrane, Synapse.
Positive control
Rat brain tissue lysates, PANC-1, F9, rat brain tissue, rat cerebellum tissue, A549.