![AffiAB® Anti-SUN1 Antibody [JG95-31]](/web/image/product.product/88963/image_1024/%5BAFG-HB-3731%5D%20AffiAB%C2%AE%20Anti-SUN1%20Antibody%20%5BJG95-31%5D%20?unique=a48b62f)
AffiAB® Anti-SUN1 Antibody [JG95-31]
UNC84A (UNC84 homolog A) , also known as SUN1, is a multi-pass nuclear membrane protein that is involved in nuclear anchoring and migration. Highly expressed in heart, brain and testis, UNC84A functions as an A-type Lamin-binding protein that forms a link between the inner and outer nuclear envelope membranes. This link acts as a structural bridge between the nuclear interior and the Actin cytoskeleton and is essential for proper localization of nuclear envelope proteins. Additionally, UNC84A may be involved in telomere attachment and in normal testis development. UNC84A contains one UNC84 (SUN) domain and exists as four isoforms due to alternative splicing events.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: O94901 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JG95-31
KO/KD
N/A
Species reactivity
Human, Rat
Tested applications
WB, IHC-P, IF-Cell, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human SUN1 aa 90-240 / 812.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000; IHC-P: 1:50-1:200; IF-Cell: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
90 kDa
Subcellular location
Nucleus.
Positive control
Rat kidney tissue lysates, A431, human breast tissue, human colon tissue, Hela.