AffiAB® Anti-Sudan I Antibody [Huam029]
Sudan I (also commonly known as CI Solvent Yellow 14 and Solvent Orange R) , is an organic compound, typically classified as an azo dye. Sudan I is one of the industry dyes and widely used in cosmetics, wax agent, solvent and textile. Sudan I has multiple toxicity such as carcinogenicity, mutagenicity, genotoxicity and oxidative damage. It is an intensely orange-red solid that is added to colourise waxes, oils, petrol, solvents, and polishes. Sudan I has also been adopted for colouring various foodstuffs, especially curry powder and chili powder, although the use of Sudan I in foods is now banned in many countries, because Sudan I, Sudan III, and Sudan IV have been classified as category 3 carcinogens (not classifiable as to its carcinogenicity to humans) by the International Agency for Research on Cancer. Sudan I is still used in some orange-coloured smoke formulations and as a colouring for cotton refuse used in chemistry experiments. Sudan 1 is a compound being warned of for health hazards by the EU regulation. It may cause allergic skin reactions and irritation of the skin. Exposure to the skin can happen by direct exposure to textile workers or by wearing tight-fitting textiles dyed with Sudan 1. Allergic reactions are induced when the azo dye binds to the human serum albumin (HSA) , forming a dye-HSA conjugate, which immunoglobulin E binds to, which causes a release of histamine.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
N/A
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
Huam029
KO/KD
N/A
Species reactivity
N/A
Tested applications
ELISA
Predicted species reactivity
N/A
Immunogen
Sudan I-OVA.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) .
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
ELISA: 1:250-1:16, 000
Molecular Weight
Predicted band size: 248 Da
Subcellular location
N/A
Positive control
Sudan I