AffiAB® Anti-STAM2 Antibody
Signal transducing adapter molecule 2 is a protein that in humans is encoded by the STAM2 gene. The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM) . Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: O75886 Human; SwissProt: O88811 Mouse; SwissProt: Q5XHY7 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human STAM2 450-480 aa
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1.9865 mg/mL
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000; IF-Cell: 1:200; FC: 1ug/ml
Molecular Weight
Predicted band size: 58 kDa
Subcellular location
Cytoplasm, Early endosome membrane.
Positive control
SK-OV-3 cell lysate, SK-Br-3 cell lysate, MCF-7 cell lysate, HepG2 cell lysate, Jurkat cell lysate, THP-1 cell lysate, PC-12 cell lysate, NIH/3T3 cell lysate, Siha, PC-3.