![AffiAB® Anti-SOX10 Antibody [1-11]](/web/image/product.product/88883/image_1024/%5BAFG-HB-3647%5D%20AffiAB%C2%AE%20Anti-SOX10%20Antibody%20%5B1-11%5D%20?unique=315d7a9)
AffiAB® Anti-SOX10 Antibody [1-11]
Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q04888 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
1-11
KO/KD
N/A
Species reactivity
Mouse
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human SOX10 aa 80-310.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1000
; IHC-P: 1:50
Molecular Weight
Predicted band size: 50 kDa
Subcellular location
Nucleus, cytoplasm
Positive control
F9, mouse fetal brain