AffiAB® Anti-SNX5 Antibody [JE64-96]

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CAT# AFG-HB-3637
Size: 100 μL

496.50 496.5 USD 496.50

496.50

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AffiAB® Anti-SNX5 Antibody [JE64-96]

Sorting nexin-5 is a protein that in humans is encoded by the SNX5 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein is a component of the mammalian retromer complex, which facilitates cargo retrieval from endosomes to the trans-Golgi network. It has also been shown to bind to the Fanconi anemia, complementation group A protein. This gene results in two transcript variants encoding the same protein. Model organisms have been used in the study of SNX5 function.

Antibody type

Recombinant Rabbit monoclonal Antibody

Uniprot ID

SwissProt: Q9Y5X3 Human; SwissProt: Q9D8U8 Mouse; SwissProt: B1H267 Rat

Recombinant

YES

Conjugation

Non-conjugated

Host

Rabbit

Isotype

IgG

Clone

JE64-96

KO/KD

N/A

Species reactivity

Human, Mouse, Rat

Tested applications

WB, IHC-P

Predicted species reactivity

N/A

Immunogen

Recombinant protein within human SNX5 aa 1-150/404.

Storage

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

N/A

Recommended dilutions

WB: 1:500 ; IHC-P: 1:100-1:400

Molecular Weight

Predicted band size: 47 kDa

Subcellular location

Cytoplasm, Endosome, Early endosome, Early endosome membrane, Cell membrane, Cytoplasmic vesicle membrane, phagocytic cup, ruffle.

Positive control

Mouse spleen tissue lysate, rat spleen tissue lysate, Jurkat cell lysate, 293T cell lysate, Hela cell lysate, HepG2 cell lysate, rat kidney tissue, human lymph nodes tissue, human thyroid carcinoma tissue, mouse kidney tissue.