AffiAB® Anti-SMAD3 Antibody

https://www.affiab.com/web/image/product.template/116016/image_1920?unique=c53b564
(0 review)

CAT# AFG-HB-3609
Size: 100 μL

433.50 433.5 USD 433.50

433.50

For Price Contact info@affigen.com

This combination does not exist.

Terms and Conditions
30-day money-back guarantee
Shipping: 2-3 Business Days

AffiAB® Anti-SMAD3 Antibody

Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1) , Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.

Antibody type

Rabbit polyclonal Antibody

Uniprot ID

SwissProt: P84022 Human

Recombinant

NO

Conjugation

Non-conjugated

Host

Rabbit

Isotype

IgG

Clone

N/A

KO/KD

N/A

Species reactivity

Human, Mouse, Rat, Zebrafish

Tested applications

WB, IF-Cell, IHC-P, FC

Predicted species reactivity

N/A

Immunogen

Synthetic peptide within N-terminal human SMAD3.

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 mg/mL.

Purity

Immunogen affinity purified.

Signal pathway

N/A

Recommended dilutions

IF-Cell: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100; WB: 1:500-1:1, 000

Molecular Weight

48 kDa

Subcellular location

Cytoplasm, Nucleus, endoplasmic reticulum

Positive control

Hela, HCT116, HepG2, human colon cancer tissue, human lung carcinoma tissue, human breast carcinoma tissue, human liver tissue, human stomach carcinoma tissue.