AffiAB® Anti-Shiga toxin subunit B Antibody
Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, whose genes are considered to be part of the genome of lambdoid prophages. Shiga toxin contains a single subunit A and five copies of subunit B. The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q7BQ98 Shigella dysenteriae
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
N/A
Tested applications
WB, ELISA
Predicted species reactivity
N/A
Immunogen
Full length protein of shiga toxin subunit B.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:2, 000-1:5, 000 ELISA 1:1, 000- 1:5, 000
Molecular Weight
8kDa
Subcellular location
N/A
Positive control
Full length recombinant protein of shiga toxin subunit B