AffiAB® Anti-SH3PX1 Antibody
This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, but does contain a SRC homology domain near its N-terminus. The encoded protein is reported to have a variety of interaction partners, including of adaptor protein 2 , dynamin, tyrosine kinase non-receptor 2, Wiskott-Aldrich syndrome-like, and ARP3 actin-related protein 3. The encoded protein is implicated in several stages of intracellular trafficking, including endocytosis, macropinocytosis, and F-actin nucleation.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q9Y5X1 Human; SwissProt: Q91VH2 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human SH3PX1 aa 430-595.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000
; IHC-P: 1:100-1:500
; FC: 1:500-1:1, 000
Molecular Weight
67 kDa
Subcellular location
Trans-Golgi network, Cell membrane, Cytoplasmic vesicle membrane, Clathrin-coated vesicle, Ruffle, Cytoplasm.
Positive control
Hela cell lysate, 293T cell lysate, NIH/3T3 cell lysate, mouse heart tissue lysate, rat smooth muscle tissue lysate, rat uterus tissue, human placenta tissue, mouse testis tissue, Hela.