![AffiAB® Anti-SFRP4 Antibody [JE41-41]](/web/image/product.product/88799/image_1024/%5BAFG-HB-3560%5D%20AffiAB%C2%AE%20Anti-SFRP4%20Antibody%20%5BJE41-41%5D%20?unique=a48b62f)
AffiAB® Anti-SFRP4 Antibody [JE41-41]
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q6FHJ7 Human; SwissProt: Q9Z1N6 Mouse; SwissProt: Q9JLS4 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE41-41
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human SFRP4 aa 181-320 / 346.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000
; FC: 1:50-1:100
Molecular Weight
40 kDa
Subcellular location
Secreted.
Positive control
Mouse testis tissue, A549, HepG2, SH-SY-5Y.