AffiAB® Anti-SF3A1 Antibody
Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes. This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP) . U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q15459 Human; SwissProt: Q8K4Z5 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human SF3A1 aa 744-793.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500
; IHC-P: 1:500
Molecular Weight
Predicted band size: 89 kDa
Subcellular location
Nucleus, Nucleus speckle.
Positive control
HL-60 cell lysate, Daudi cell lysate, Hela cell lysate, 293T cell lysate, mouse ovary tissue, Hela.