AffiAB® Anti-SERPING1 Antibody
Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P05155 Human; SwissProt: P97290 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human SERPING1 aa 145-403.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Cardiovascular
Recommended dilutions
WB: 1:500-1:1, 000
; IHC-P: 1:200-1:1000
Molecular Weight
55 kDa
Subcellular location
Secreted.
Positive control
HepG2 cell lysate, HL-60 cell lysate, human liver tissue, human placenta tissue, mouse liver tissue.