AffiAB® Anti-Rho A+B+C Antibody [SR38-00]

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CAT# AFG-HB-3410
Size: 100 μL

496.50 496.5 USD 496.50

496.50

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AffiAB® Anti-Rho A+B+C Antibody [SR38-00]

Transforming protein RhoA, also known as Ras homolog family member A (RhoA) , is a small GTPase protein in the Rho family of GTPases that in humans is encoded by the RHOA gene. RhoA, and the other Rho GTPases, are part of a larger family of related proteins known as the Ras superfamily, a family of proteins involved in the regulation and timing of cell division. RhoA specifically is regarded as a prominent regulatory factor in other functions such as the regulation of cytoskeletal dynamics, transcription, cell cycle progression and cell transformation. Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene. RHOB is a member of the Rho GTP-binding protein family. RhoC (Ras homolog gene family, member C) is a small (~21 kDa) signaling G protein (more specifically a GTPase) , and is a member of the Rac subfamily of the family Rho family of GTPases. It is encoded by the gene RHOC.

Antibody type

Recombinant Rabbit monoclonal Antibody

Uniprot ID

SwissProt: P08134 Human; SwissProt: P61586 Human; SwissProt: P62745 Human; SwissProt: P62746 Mouse; SwissProt: Q62159 Mouse; SwissProt: Q9QUI0 Mouse; SwissProt: P61589 Rat; SwissProt: P62747 Rat

Recombinant

YES

Conjugation

Non-conjugated

Host

Rabbit

Isotype

IgG

Clone

SR38-00

KO/KD

N/A

Species reactivity

Human, Mouse

Tested applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Predicted species reactivity

Rat

Immunogen

Recombinant protein within Human RhoC aa aa 1-193 / 193.

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

N/A

Recommended dilutions

WB: 1:500; IF-Cell: 1:50; IF-Tissue: 1:50; IHC-P: 1:50; FC: 1:50

Molecular Weight

Predicted band size: 22 kDa

Subcellular location

Cytoplasm, Nucleus, Cell membrane, Cleavage furrow.

Positive control

HepG2 cell lysate, Hela cell lysate, Jurkat cell lysate, AGS, HepG2, NIH/3T3, human stomach carcinoma tissue, mouse colon tissue, mouse stomach tissue.