AffiAB® Anti-RbBP5 Antibody [PSH0-15]
Retinoblastoma-binding protein 5 is a protein that in humans is encoded by the RBBP5 gene. The protein encoded by this gene is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q15291 Human; SwissProt: Q8BX09 Mouse; Entrez Gene: 304794 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
PSH0-15
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human RbBP5 aa 431-480 / 538.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000
Molecular Weight
Predicted band size: 59 kDa
Subcellular location
Nucleus.
Positive control
SW480 cell lysate, A431 cell lysate, C2C12 cell lysate, 293 cell lysate, MCF-7 cell lysate, NIH/3T3 cell lysate, K562 cell lysate, N2A cell lysate, PC-12 cell lysate, RAW264.7 cell lysate.