AffiAB® Anti-RAB27B Antibody
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion ref. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 ref. May be involved in targeting uroplakins to urothelial apical membranes (By similarity) .
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: O00194 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide with N-terminal Human RAB27B.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB:1:500
; FC:1:500-1:1, 000
Molecular Weight
Predicted band size: 25 kDa
Subcellular location
Late endosome, Membrane, Lipid-anchor.
Positive control
U937 cell lysates, SH-SY5Y.