AffiAB® Anti-PYCR1 Antibody
This gene encodes an enzyme that catalyzes the NAD (P) H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP (+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P32322 Human; SwissProt: Q922W5 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within C-terminal Human PYCR1.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 1% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB:1:500-1:1, 000
; IHC-P:1:100-1:500
Molecular Weight
33 kDa
Subcellular location
Mitochondrion.
Positive control
HepG2 cell lysates, rat large intestine tissue, mouse brain tissue, human pancreas tissue.