![AffiAB® Anti-PSMA1 Antibody [JU66-24]](/web/image/product.product/77735/image_1024/%5BAFG-HB-3278%5D%20AffiAB%C2%AE%20Anti-PSMA1%20Antibody%20%5BJU66-24%5D%20?unique=d31c23b)
AffiAB® Anti-PSMA1 Antibody [JU66-24]
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome. Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P25786 Human; SwissProt: Q9R1P4 Mouse; SwissProt: P18420 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JU66-24
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human PSMA1 aa 214-263 / 263.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Parkinson’s disease, Huntington's disease, Amyotrophic lateral sclerosis, Alzheimer disease
Recommended dilutions
WB: 1:500-1:2, 000; IF-Cell: 1:100-1:500; IF-Tissue: 1:100-1:500; IHC-P: 1:50-1:200; FC: 1:50-1:100; IP: Use at an assay dependent concentration.
Molecular Weight
30 kDa
Subcellular location
Nucleus, Cytoplasm.
Positive control
Jurkat cell lysate, Hela cell lysate, HepG2 cell lysate, 293 cell lysate, PC-12 cell lysate, mouse spleen tissue lysate, rat spleen tissue lysate, HepG2, PC-3M, human liver carcinoma tissue, rat testis tissue, mouse cerebellum tissue, human pancreas tissue.