![AffiAB® Anti-PSD95 Antibody [B5-E6]](/web/image/product.product/77729/image_1024/%5BAFG-HB-3272%5D%20AffiAB%C2%AE%20Anti-PSD95%20Antibody%20%5BB5-E6%5D%20?unique=315d7a9)
AffiAB® Anti-PSD95 Antibody [B5-E6]
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: P78352 Human; SwissProt: Q62108 Mouse; SwissProt: P31016 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2b
Clone
B5-E6
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within N-terminal human PSD95.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Huntington's disease, Neuroscience
Recommended dilutions
WB: 1:2, 000-1:5, 000; IF-Cell: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
80 kDa
Subcellular location
Cell membrane, postsynaptic density, synapse, Cytoplasm, axon, dendritic spine, dendrite, presynapse.
Positive control
SHG-44 cell lysate, A172 cell lysate, N2A cell lysate, N2A, rat brain tissue, mouse brain tissue, Hela.