![AffiAB® Anti-PSD93 Antibody [JM41-04]](/web/image/product.product/77727/image_1024/%5BAFG-HB-3270%5D%20AffiAB%C2%AE%20Anti-PSD93%20Antibody%20%5BJM41-04%5D%20?unique=a48b62f)
AffiAB® Anti-PSD93 Antibody [JM41-04]
Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q15700 Human; SwissProt: Q91XM9 Mouse; SwissProt: Q63622 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JM41-04
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, FC, IP
Predicted species reactivity
Mouse, Rat
Immunogen
Synthetic peptide within human PSD93 aa 600-660.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Neuroscience
Recommended dilutions
WB: 1:500-1:2, 000
; FC: 1:50-1:100
; IP: Use at an assay dependent concentration.
Molecular Weight
Predicted band size: 98 kDa
Subcellular location
Cell junction, Cell membrane, Cell projection, Membrane, Synapse.
Positive control
Hela cell lysate, SH-SY5Y cell lysate, SH-SY5Y.