AffiAB® Anti-Prostate Specific Antigen Antibody [SD07-45]

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CAT# AFG-HB-3254
Size: 100 μL

496.50 496.5 USD 496.50

496.50

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AffiAB® Anti-Prostate Specific Antigen Antibody [SD07-45]

Prostate specific antigen (PSA) , also designated γ-seminoprotein, seminin, p30 antigen, semenogelase, and kallikrein 3 (KLK3) , was first identified as a glycoprotein in human seminal plasma. PSA was determined by sequence similarity to be a member of the kallikrein subfamily of trypsin proteases. PSA is a serine protease that hydrolyzes the major human seminal protein, the seminal plasma mobility inhibitor precursor, or semenogelin I (SPMIP or SgI) , which leads to semen liquification. PSA production and expression are highest in normal, benign hyperplastic and cancerous tissues of the prostate, although PSA has also been detected in accessory male sex glands and in breast cancer. PSA has been identified as an aid in the early detection of prostate cancer and is a commonly used tumor marker.

Antibody type

Recombinant Rabbit monoclonal Antibody

Uniprot ID

SwissProt: P07288 Human

Recombinant

YES

Conjugation

Non-conjugated

Host

Rabbit

Isotype

IgG

Clone

SD07-45

KO/KD

N/A

Species reactivity

Human

Tested applications

WB, IF-Cell, IF-Tissue, IHC-P

Predicted species reactivity

N/A

Immunogen

Recombinant protein within human Prostate Specific Antigen aa 198-261/261.

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

Cancer

Recommended dilutions

WB: 1:1, 000; IF-Cell: 1:50-1:200; IF-Tissue: 1:50-1:200; IHC-P: 1:50-1:200

Molecular Weight

34 kDa

Subcellular location

Secreted.

Positive control

PC-3M, human prostate tissue, human prostate carcinoma tissue.