AffiAB® Anti-Prealbumin Antibody [3-E11]
Transthyretin (TTR) originally called prealbumin is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol. Prealbumin concentrations are disproportionately high in human ventricular cerebrospinal fluid (CSF) . Over 80 different disease-causing mutations in prealbumin have been reported. TTR is known to be associated with the amyloid diseases senile systemic amyloidosis (SSA) , familial amyloid polyneuropathy (FAP) , and familial amyloid cardiomyopathy (FAC) .
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: P02766 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2b
Clone
3-E11
KO/KD
N/A
Species reactivity
Human
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human Prealbumin PA aa 100-147.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Neuroscience, Cardiovascular
Recommended dilutions
WB: 1:5, 000
Molecular Weight
16 kDa
Subcellular location
secreted
Positive control
Human plasma