AffiAB® Anti-PPP3CC Antibody
Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P48454 Human; SwissProt: P48455 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human PPP3CC aa 1-200.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
VEGF signaling pathway, Neuroscience, Calcium signaling pathway, Immunology & Inflammation, Alzheimer disease, MAPK signaling pathway, Amyotrophic lateral sclerosis, cGMP-PKG signaling pathway
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:50-1:100; IHC-P: 1:100-1:500
Molecular Weight
58 kDa
Subcellular location
Cytosol, presynaptic cytosol, mitochondrion, calcineurin complex, cytoplasm, glutamatergic synapse.
Positive control
HepG2 cell lysate, mouse hippocampus tissue lysate, HepG2, mouse testis tissue.