AffiAB® Anti-PPP2R5B Antibody
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform is an enzyme that in humans is encoded by the PPP2R5B gene. The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. Highest expression in brain.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q15173 Human; SwissProt: Q6PD28 Mouse; SwissProt: Q80W83 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human PPP2R5B aa 1-250.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2.1 mg/ml
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000
; IHC-P: 1:600
; FC: 1:500-1:1, 000
Molecular Weight
Predicted band size: 57 kDa
Subcellular location
Cytoplasm.
Positive control
Mouse cerebellum tissue lysate, human cerebellum tissue lysate, rat cerebellum tissue lysate, SH-SY5Y cell lysates, human colon tissue, SH-SY5Y.