AffiAB® Anti-Plakophilin 3 Antibody
Plakophilin-3 is a protein that in humans is encoded by the PKP3 gene.This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q9Y446 Human; SwissProt: Q9QY23 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within C-terminal human Plakophilin 3.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:50-1:200; IHC-P: 1:500-1:2, 000
Molecular Weight
Predicted band size: 87 kDa.
Subcellular location
Cell junction, Nucleus.
Positive control
SKBR-3 cell lysates, SW620, rat tongue tissue, human skin tissue, human breast carcinoma tissue.