![AffiAB® Anti-Pirh2 Antibody [JE55-39]](/web/image/product.product/77609/image_1024/%5BAFG-HB-3145%5D%20AffiAB%C2%AE%20Anti-Pirh2%20Antibody%20%5BJE55-39%5D%20?unique=a48b62f)
AffiAB® Anti-Pirh2 Antibody [JE55-39]
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q96PM5 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE55-39
KO/KD
N/A
Species reactivity
Human
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within N-terminal Human Pirh2.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
p53 signaling pathway, Cancer
Recommended dilutions
WB: 1:500-1:2, 000
Molecular Weight
30 kDa
Subcellular location
Nucleus, Nucleus speckle, Cytoplasm.
Positive control
293T cell lysates.