![AffiAB® Anti-Phospho-GATA3 (S308) Antibody [ST44-09]](/web/image/product.product/77508/image_1024/%5BAFG-HB-3036%5D%20AffiAB%C2%AE%20Anti-Phospho-GATA3%20%28S308%29%20Antibody%20%5BST44-09%5D%20?unique=a48b62f)
AffiAB® Anti-Phospho-GATA3 (S308) Antibody [ST44-09]
GATA-3 antibody (GATA binding protein 3) is a member of the GATA family of transcription factors. GATA-3 appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 has a strong association with estrogen receptor-alpha expression in breast cancer and evidence exists that GATA-3 may be used to predict response to hormonal therapy of breast cancer patients. GATA-3 has also been shown to be a novel marker for bladder cancer. In one study, GATA-3 stained 67% of 308 urothelial carcinomas but no prostate or renal carcinomas.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P23771 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
ST44-09
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IHC-P, IP
Predicted species reactivity
N/A
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser308 of Human GATA3 aa 281-330 / 443.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
allergic rhinitis, Cardiovascular
Recommended dilutions
WB: 1:1, 000-1:2, 000
; IHC-P: 1:50-1:200
; IP: Use at an assay dependent concentration.
Molecular Weight
Predicted band size: 48 kDa
Subcellular location
Nucleus.
Positive control
Human skin tissue lysate, Jurkat cell lysate.