![AffiAB® Anti-PGP9.5 Antibody [B1-5-6]](/web/image/product.product/77463/image_1024/%5BAFG-HB-2990%5D%20AffiAB%C2%AE%20Anti-PGP9.5%20Antibody%20%5BB1-5-6%5D%20?unique=8544d55)
AffiAB® Anti-PGP9.5 Antibody [B1-5-6]
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: P09936 Human; SwissProt: Q9R0P9 Mouse; SwissProt: Q00981 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2a
Clone
B1-5-6
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, IF-Cell, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human PGP95 aa 174-223 / 223.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Parkinson’s disease, Neuroscience
Recommended dilutions
WB: 1:500; IF-Cell: 1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
Predicted band size: 25 kDa
Subcellular location
Cytoplasm. Endoplasmic reticulum.
Positive control
A172, SHG-44, A549, SH-SY5Y, rat cerebellum tissue, human kidney tissue, human pancreas tissue, mouse brain tissue.