![AffiAB® Anti-PGD Antibody [JE56-26]](/web/image/product.product/77459/image_1024/%5BAFG-HB-2986%5D%20AffiAB%C2%AE%20Anti-PGD%20Antibody%20%5BJE56-26%5D%20?unique=a48b62f)
AffiAB® Anti-PGD Antibody [JE56-26]
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P52209 Human; SwissProt: Q9DCD0 Mouse; SwissProt: P85968 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE56-26
KO/KD
N/A
Species reactivity
Human, Mouse, Rat, Zebrafish
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within C-terminal Human PGD.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000; IF-Cell: 1:50-1:100; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
Predicted band size: 53 kDa.
Subcellular location
Cytoplasm.
Positive control
Mouse liver tissue lysate, mouse placenta tissue lysate, rat spleen tissue lysate, rat testis tissue lysate, mouse brain tissue lysate, zebrafish tissue lysates, A549, rat spleen tissue, mouse testis tissue.