AffiAB® Anti-PER1 Antibody
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: O15534 Human; SwissProt: O35973 Mouse; SwissProt: Q8CHI5 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human PER1 aa 320-519.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000; IF-Cell: 1:50-1:100; IHC-P: 1:100-1:500; FC: 1:500-1:1, 000
Molecular Weight
Predicted band size: 136 kDa.
Subcellular location
Nucleus, Cytoplasm.
Positive control
293T cell lysate, Hela cell lysate, Daudi cell lysate, mouse pancreas tissue lysate, rat brain tissue lysate, Hela, rat kidney tissue, Hela.