AffiAB® Anti-Peptide YY Antibody
Peptide YY (PYY) also known as peptide tyrosine tyrosine is a peptide that in humans is encoded by the PYY gene. Peptide YY is a short (36-amino acid) peptide released from cells in the ileum and colon in response to feeding. In the blood, gut, and other elements of periphery, PYY acts to reduce appetite; similarly, when injected directly into the central nervous system, PYY is also anorexigenic, i.e., it reduces appetite.Dietary fibers from fruits, vegetables, and whole grains, consumed, increase the speed of transit of intestinal chyme into the ileum, to raise PYY3-36, and induce satiety. Peptide YY can be produced as the result of enzymatic breakdown of crude fish proteins and ingested as a food product.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P10082 Human; SwissProt: Q9EPS2 Mouse; SwissProt: P10631 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within N-terminal human Peptide YY.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000; IF-Cell: 1:200; FC: 1:100-1:500
Molecular Weight
Predicted band size: 11 kDa.
Subcellular location
Secreted.
Positive control
Human small intestine tissue lysate, RAW264.7 cell lysate, rat liver tissue lysate, SW620, SiHa.